When it comes to improving your sexual health and performance, few treatments are as promising as the P-Shot (Priapus Shot). This procedure uses platelet-rich plasma (PRP) from your own blood to naturally enhance tissue regeneration, blood flow, and sensitivity in the penis. But here’s the catch: not all PRP is created equal. The effectiveness of your P-Shot depends heavily on the quality of the PRP used and the skill of the provider administering it.
At Genesis Lifestyle Medicine, our approach to men’s sexual health combines advanced PRP technology with the highest standards of care. Our providers are trained in regenerative medicine and ensure that every step, from PRP preparation to injection, is performed with precision. Here are six key questions to ask before your P-Shot to make sure you’re getting the best possible PRP quality and outcome.
1. How do you prepare the PRP?
The preparation of PRP plays a major role in the effectiveness of your P-Shot. During the process, your blood is drawn and spun in a centrifuge to separate plasma rich in platelets and growth factors. However, different clinics use different equipment, and not all systems yield the same quality of platelets for injection.

Ask your provider which PRP system they use and whether it’s FDA-approved or clinically validated. High-quality PRP systems ensure the correct platelet concentration and maintain sterile conditions. The more concentrated your PRP is, the greater its regenerative potential. At Genesis Lifestyle Medicine, we use advanced PRP preparation protocols to deliver high platelet concentrations.
2. What is the concentration of platelets in the PRP?
Not every “platelet-rich plasma” sample actually contains a therapeutic amount of platelets. Some low-quality systems may produce PRP that’s only two to three times the baseline platelet count, while other systems can achieve up to fifteen times the concentration.
Platelets release potent growth factors that stimulate blood vessel formation and collagen production, both vital for erectile tissue rejuvenation. The more precisely the concentration is controlled, the more consistent your results will be. Don’t hesitate to ask your provider what concentration range they typically achieve. A well-trained specialist can explain how their method optimizes outcomes.
3. What sterilization and safety protocols do you follow?
Because PRP involves injections into sensitive tissue, maintaining strict sterility is essential. Contamination at any stage, from blood draw to injection, can increase the risk of infection or inflammation. A reputable medical clinic will have dedicated cleanroom procedures, sterile PRP kits, and properly trained medical professionals.
You should always feel comfortable asking how the clinic ensures sterility and what safety measures are in place. At Genesis Lifestyle Medicine, every P-Shot is performed by a licensed medical provider in a clinical-grade setting using single-use sterile equipment. Our patient safety standards meet or exceed national medical guidelines to ensure optimal results.

4. How experienced is your provider with PRP and P-Shot treatments?
Even the best PRP won’t deliver results without expert technique. The P-Shot requires precision and a deep understanding of male sexual health. You should always ask your provider how long they’ve been performing PRP-based treatments and how many P-Shots they’ve administered.
An experienced provider will not only know where and how to inject but also how to tailor treatment to your unique health profile. At Genesis Lifestyle Medicine, our providers are trained in regenerative and sexual medicine and have extensive experience in PRP therapies. We use ultrasound-guided techniques when needed to ensure accuracy and maximize your comfort.
5. How will you personalize my treatment for the best results?
High-quality PRP is only part of the equation: personalization is the rest. Your age, hormone balance, blood quality, and overall health all influence how your body responds to PRP therapy. A one-size-fits-all approach simply won’t work for everyone.
Ask your provider whether they will perform lab work or evaluate your hormone and nutritional status before your P-Shot. Some men benefit from combining PRP therapy with testosterone optimization (TRT) or GAINSWave® therapy to enhance circulation and nerve sensitivity. At Genesis Lifestyle Medicine, we believe in following a comprehensive, inside-out approach to men’s sexual wellness to optimize your body’s natural regenerative capacity.
6. What results can I realistically expect after my P-Shot?
One of the most important discussions you can have with your provider is about results. Because the P-Shot relies on your body’s own platelet growth factors, outcomes depend on factors such as your age, overall health, circulation, and hormonal balance. Some men notice improvements within a few weeks, while others may need additional sessions for full results.

A trustworthy provider will set realistic expectations and explain the typical treatment timeline. At Genesis Lifestyle Medicine, we emphasize transparency and ongoing follow-up. Your provider will review your progress, recommend when to schedule any maintenance sessions, and help you track improvements in function and satisfaction over time.
Choose a clinic that values quality as much as you do
Your P-Shot results depend on more than just the injection: they rely on science, precision, and the provider’s commitment to excellence. High-quality PRP can mean the difference between temporary improvement and long-lasting rejuvenation.
When you choose Genesis Lifestyle Medicine, you’re choosing a team that’s committed to medical integrity. Our clinics across the U.S. specialize in helping men restore performance through a combination of regenerative medicine, hormone therapy, and personalized care. Schedule your consultation today to learn more about how the P-Shot, when done right, can help you feel like yourself again.


