You decided to take a proactive step toward improving your sexual performance with the P-Shot. But after weeks or even months, you’re wondering why things haven’t changed much. Maybe your erections feel the same, your stamina hasn’t improved, or your confidence feels shaky. It’s natural to feel discouraged when expectations don’t match results, but all hope isn’t lost.
At Genesis Lifestyle Medicine, we understand that regenerative therapies like the P-Shot take time and careful follow-through. Our goal is to help you understand what might be happening inside your body, why results can vary, and how to get the most out of your treatment. Here’s what to know (and what to do next) if you’re not seeing the results you hoped for.
Signs your P-Shot may not be working
It’s important to remember that the P-Shot works by stimulating your body’s natural repair and regeneration processes. This takes time, and improvement often happens gradually rather than all at once. Still, some signs may suggest that your body needs more support. If you notice any of the following changes (or lack thereof), it could mean your P-Shot may need adjustment:
- No noticeable improvement in erection firmness or sexual stamina after 8-12 weeks
- Difficulty maintaining erections during sexual activity
- Little to no change in sexual desire or arousal
- Persistent performance anxiety or reduced confidence
- Ongoing curvature or discomfort associated with Peyronie’s disease
- No improvement in sensitivity or overall satisfaction during intimacy
These signs don’t necessarily mean your P-Shot “didn’t work.” Instead, they’re often signals that your body’s healing response is slower or that additional factors are influencing your results.
Reasons why your P-Shot may not be working
Every man’s body responds differently to regenerative treatments. Factors like blood circulation, hormone balance, and overall health play a major role in how your body reacts to PRP therapy. Here are some of the most common reasons your P-Shot results might take longer to appear:
- Underlying health conditions such as diabetes, hypertension, or high cholesterol
- Poor blood circulation that limits nutrient and oxygen flow to the penile tissue
- Hormonal imbalances, including low testosterone levels
- Lifestyle habits such as smoking, excessive alcohol, poor sleep, or chronic stress
- Inconsistent follow-up care or missed maintenance treatments
- Lower platelet concentration or suboptimal PRP preparation technique
- Long-term or severe erectile dysfunction that requires combination therapy
At Genesis Lifestyle Medicine, we evaluate these factors comprehensively to understand what your body needs for effective healing and optimal sexual function.
How to make P-Shot work effectively
While the P-Shot’s regenerative benefits can take time to develop, there are many ways to support your body and enhance your outcome. A combination of medical guidance, healthy lifestyle choices, and proper follow-up can help maximize your results.
Schedule a follow-up consultation
If it’s been several weeks since your P-Shot and you've made little progress, schedule a follow-up visit. Your provider can assess your bloodwork, review your injection results, and determine whether a booster treatment or complementary therapy is needed. Sometimes, adjusting the PRP concentration or technique makes a noticeable difference.
Optimize your overall health
Blood circulation is the foundation of healthy erections. Managing chronic conditions like diabetes or high blood pressure, improving your diet, exercising regularly, and getting sufficient rest all play a role in blood circulation and tissue repair. The better your cardiovascular health, the more responsive your body will be to the P-Shot.
Support hormone balance
If your testosterone levels are low, your body may not fully respond to regenerative treatments. Combining the P-Shot with testosterone replacement therapy (TRT) can help restore hormonal balance, enhance libido, and improve energy and mood for better sexual performance. At Genesis Lifestyle Medicine, we can help you achieve balanced testosterone levels.
Combine treatments for synergistic results
Many men benefit from pairing the P-Shot with complementary therapies. For example, GAINSWave® therapy uses acoustic waves to increase blood circulation and stimulate tissue regeneration, while TriMix injections or oral medications may help achieve firmer erections more quickly during the regenerative process. This multi-therapy approach can help address different aspects of sexual function, leading to more comprehensive results.
Maintain healthy habits
Your lifestyle has a profound effect on your sexual health. Limiting alcohol, avoiding tobacco, managing stress, and prioritizing quality sleep all promote better blood flow and faster recovery. Nutrient-rich foods that support vascular health, such as leafy greens and omega-3-rich fish, can also make a significant difference and improve sexual wellness.
Be patient and consistent
Regenerative treatments are not instant fixes: they rely on your body’s natural ability to heal and rebuild. For some men, noticeable improvements appear within a few weeks; for others, the benefits continue to develop over several months. Consistency in follow-ups and adherence to your provider’s guidance are essential to achieving optimal outcomes.
Not seeing immediate results from your P-Shot doesn’t mean it hasn’t worked; it may simply mean your body needs more time or additional support to activate its full regenerative potential.
At Genesis Lifestyle Medicine, we take a whole-body approach to men’s sexual wellness, combining advanced regenerative medicine with hormone optimization and lifestyle guidance to help you feel and perform your best. Our providers will work with you to identify what’s standing in the way of your results and design a plan that helps you achieve lasting improvements in sexual vitality and overall health.
