For many people, losing weight is not just about counting calories but about unlocking the body’s natural ability to burn fat efficiently, control cravings, and maintain energy throughout the day. One compound gaining attention for its role in these processes is NAD+ (nicotinamide adenine dinucleotide), a coenzyme found in every cell of your body. NAD+ plays a key role in metabolism, cellular repair, and energy production, which are essential for weight loss.
At Genesis Lifestyle Medicine, we harness science-backed treatments to help you achieve your goals from the inside out. In this article, we’ll explore how NAD+ can support weight loss and share tips to help you get the best results. Whether you’re new to NAD+ therapy or considering adding it to your wellness plan, here’s what you need to know.
How NAD+ can help promote weight loss
Boosting your metabolism
Your metabolism is the engine that determines how efficiently your body turns food into energy. NAD+ is essential for activating enzymes that break down carbohydrates, fats, and proteins into usable fuel (ATP). When NAD+ levels are optimal, your metabolic rate can increase, allowing you to burn calories more effectively, even at rest. This not only accelerates fat loss but also helps prevent the sluggishness that often accompanies calorie-restricted diets.
Supporting fat oxidation
Burning stored fat for energy (known as fat oxidation) is a cornerstone of weight loss. NAD+ activates a group of proteins called sirtuins, which help regulate fat metabolism and encourage your body to use fat as its primary energy source. This process reduces fat storage, especially in stubborn areas, and enhances the efficiency of your workouts. Over time, improved fat oxidation can make it easier to maintain your target weight without extreme dieting.
Improving mitochondrial function
Your mitochondria are the “power plants” inside your cells. When they’re healthy and efficient, your body can produce more energy from the same amount of fuel. NAD+ plays a direct role in supporting mitochondrial health and repair. With more efficient mitochondria, you can sustain higher activity levels, recover faster from exercise, and maintain better energy balance, which are key factors in both losing weight and keeping it off.
Helping regulate appetite
NAD+ has been linked to pathways in the brain that influence hunger and satiety. By helping regulate these appetite signals, NAD+ may reduce cravings and make it easier to stick to a balanced eating plan. It also plays a role in maintaining healthy circadian rhythms, which can impact when you feel hungry and how your body stores fat. With fewer urges to overeat and a more consistent meal schedule, weight loss becomes a smoother process.
Tips to optimize weight loss while on NAD+
Pair NAD+ therapy with regular exercise
While NAD+ can give your metabolism a boost, it works best alongside physical activity. Incorporating strength training and cardio helps you maximize calorie burn, improve muscle tone, and increase your metabolic rate long-term. High-intensity interval training (HIIT) can be especially effective, as it naturally increases NAD+ levels in the body while promoting fat loss.
Follow a nutrient-rich, balanced diet
For NAD+ to do its job effectively, your body needs the right building blocks, especially B vitamins, which are essential for NAD+ production. Focus on whole foods like lean proteins, leafy greens, berries, nuts, and fatty fish. Avoid excessive processed foods and added sugars, as they can disrupt your metabolism and reduce the benefits of NAD+ therapy.
Stay consistent with treatments
NAD+ therapy works best when the levels are maintained over time. Skipping NAD+ therapy sessions or stopping abruptly can reduce its effectiveness. Work with your healthcare provider at Genesis Lifestyle Medicine to create a wellness treatment plan that aligns with your goals and keeps your NAD+ levels optimized for sustained results.
Prioritize quality sleep
Sleep is a critical yet often overlooked part of weight management. Poor sleep can disrupt appetite hormones, slow metabolism, and increase fat storage. NAD+ supports circadian rhythm regulation, but it’s up to you to maintain a healthy sleep schedule. Aim for 7 to 9 hours of quality rest each night to help your body respond optimally to NAD+ therapy.
Manage stress effectively
Chronic stress increases cortisol levels, which can lead to weight gain, especially around the midsection. While NAD+ supports cellular resilience, combining it with stress-reduction methods like meditation, yoga, or deep breathing can amplify results. Managing stress also helps regulate appetite and reduces emotional eating triggers.
NAD+ is a key player in the metabolic processes that influence how your body stores and burns fat, regulates appetite, and maintains energy. At Genesis Lifestyle Medicine, we offer NAD+ as part of a personalized approach to weight management. Our goal is to help you not only lose weight but also improve your overall health, energy, and confidence. If you’re ready to see how NAD+ can support your transformation, schedule a consultation with our team today.
