Living with fibromyalgia can feel like a never-ending cycle of discomfort and exhaustion. You may wake up already feeling tired, struggle through the day with widespread muscle pain, and fight to stay focused as brain fog clouds even the simplest thoughts.
At Genesis Lifestyle Medicine, we proudly offer NAD+ as a promising tool that may help improve cellular health and support people living with fibromyalgia. This article explores how NAD+ might play a role in helping you feel more like yourself again.
What is fibromyalgia?
Fibromyalgia is a chronic condition defined by widespread body pain, heightened sensitivity to pressure, chronic fatigue, and sleep disturbances. Many people report trouble concentrating or remembering things, a symptom commonly called “fibro fog.” Unlike injuries or localized pain, fibromyalgia doesn’t stem from one identifiable source. Instead, it involves your nervous system, your pain pathways, and your body’s ability to process and regulate signals.

Researchers believe fibromyalgia occurs due to an exaggerated response within the brain and spinal cord; essentially, your nervous system becomes overly sensitive, amplifying pain even when there is no tissue damage. The complexity of fibromyalgia makes treatment challenging, and many traditional therapies focus solely on pain management rather than addressing underlying cellular deficiencies or dysfunction.
Can NAD+ support people with fibromyalgia?
NAD+, short for nicotinamide adenine dinucleotide, is a vital coenzyme found in every cell of your body. Its primary job is to help convert nutrients into energy, repair damaged DNA, and maintain healthy brain and nerve function. However, your NAD+ levels naturally decline with age, illness, chronic stress, and inflammation, factors that overlap with fibromyalgia.
So, the question becomes: can raising NAD+ levels support your body in a way that improves fibromyalgia symptoms? While research is ongoing, emerging science suggests that lack of cellular energy, mitochondrial dysfunction, and impaired nervous system signaling may play a role in fibromyalgia. NAD+ helps address these processes at the cellular level, offering a potential pathway to relief rather than simply masking symptoms.
At Genesis Lifestyle Medicine, NAD+ therapy is available in patch, injection, and nasal spray forms. Below are several ways NAD+ may support people with fibromyalgia:
Enhancing cellular energy production
One of the most debilitating aspects of fibromyalgia is feeling exhausted even after resting. NAD+ plays a central role in the process your cells use to create ATP, the energy currency your body depends on. When NAD+ levels are low, your cells struggle to produce energy efficiently, leaving you drained. By replenishing NAD+, your body may generate energy more effectively, helping counteract persistent tiredness and chronic fatigue associated with fibromyalgia.

Supporting mitochondrial function
Your mitochondria are the powerhouses of your cells. Research suggests that many people with fibromyalgia show signs of mitochondrial dysfunction, meaning their cells have trouble operating at full capacity. NAD+ is essential for mitochondrial health and function. By increasing NAD+, your cells may be better equipped to manage stress, repair themselves, and operate more efficiently, potentially reducing discomfort and improving overall stamina.
Maintaining neurological balance
Fibromyalgia isn’t just a condition of the body: it has a strong neurological component. Pain perception, sleep quality, memory, and mood are directly linked to neurotransmitters and neural pathways. NAD+ therapy may support brain cell communication and regulate neurotransmitters involved in pain response and emotional balance. By improving cellular communication in the nervous system, NAD+ may help ease fibro fog, reduce irritability, and enhance clarity.
Encouraging cellular repair and resilience
Chronic pain conditions often involve oxidative stress and cellular damage. NAD+ contributes to DNA repair and supports proteins that protect cells from stress. Increasing NAD+ may help your body repair damage more effectively, strengthen cell structures, and reduce inflammation, all factors tied to fibromyalgia flare-ups. Over time, this may support better long-term resilience rather than temporary symptom relief.

Supporting healthy sleep cycles
Fatigue and poor sleep are defining symptoms of fibromyalgia. NAD+ influences circadian rhythms and cell signaling involved in sleep cycles. When NAD+ levels are adequate, your body may regulate sleep more effectively, helping you rest more deeply and feel more restored upon waking. More restorative sleep can, in turn, lower pain sensitivity, improve mood, and enhance daily function.
Fibromyalgia is a complex condition that affects every aspect of your life, from your energy and clarity to your confidence. While no single treatment works for everyone, addressing your body at the cellular level offers a promising new direction for lasting relief.
At Genesis Lifestyle Medicine, we are committed to solutions that support your whole-body health and offer NAD+ through patches, injections, and nasal sprays as part of a personalized treatment plan. If you’re searching for a more comprehensive approach to fibromyalgia care, NAD+ may offer the support your body needs. Schedule your consultation today.


