You may not notice hormonal changes right away, but over time, they can quietly reshape your sexual health. Maybe you’ve felt your libido slipping, erections becoming less dependable, or sexual satisfaction declining. These changes often stem from shifts in key male hormones rather than anything you’re “doing wrong.”
At Genesis Lifestyle Medicine, our expert team understands how deeply these changes can impact your life. We offer regenerative treatments like the P-Shot to address sexual concerns and help you reclaim optimal well-being. In this article, you’ll learn exactly how hormones influence your sexual function, and how the P-Shot can help restore sensitivity.
How hormones affect men’s sexual function
Hormones regulate nearly every aspect of male sexual performance. When they drift out of balance due to aging, stress, lifestyle factors, or medical conditions, sexual function often declines in predictable ways.

Testosterone regulates libido
Testosterone drives sexual desire, motivation, and overall interest in intimacy. When levels fall, you may feel less mentally stimulated by sexual activity, struggle to initiate, or notice that sexual thoughts become less frequent. Even mild declines in testosterone can change how often you feel “in the mood,” altering the rhythm of your sexual life.
Hormones influence erectile function
Male hormones support the vascular, neurological, and muscular processes required for an erection. Low testosterone or hormonal imbalances can decrease nitric oxide production, lower blood flow, and reduce the firmness or duration of erections. This often leads to inconsistent results, performance anxiety, or the need for increased stimulation to maintain an erection.
Hormonal shifts affect penile sensitivity
Age-related hormonal decline can reduce nerve responsiveness and blood supply to penile tissue, leading to diminished sensation. You may even notice it takes longer to feel arousal, or pleasurable sensations become muted. This loss of sensitivity can affect your performance, orgasm intensity, and overall enjoyment.
Hormones influence ejaculation and stamina
Balanced hormone levels support optimal energy, muscle function, and neurological signaling. When hormones dip, you may experience delayed ejaculation, reduced stamina, or decreased endurance during sexual activity. Fatigue, a common result of low testosterone, can make sex feel more effortful and less spontaneous.
How the P-Shot can help
The P-Shot (Priapus Shot®) is a regenerative treatment that uses platelet-rich plasma (PRP) from your own blood to support better sexual performance and penile health. Because PRP is rich in growth factors, it encourages targeted healing, new tissue development, and improved blood supply, all essential components of strong sexual function.

The P-Shot is one of the most effective natural options for men seeking enhanced erectile quality and sensitivity. Here’s how it can help with men’s sexual function:
Stimulate natural tissue regeneration
The P-Shot delivers concentrated growth factors directly into the penile tissue. These growth factors signal your body to repair, rebuild, and regenerate tissue, strengthening the vascular and structural elements required for optimal erections. Over time, healthier tissue contributes to improved rigidity, responsiveness, and stamina.
Improve blood flow for stronger erections
Because the P-Shot boosts angiogenesis, the creation of new blood vessels, it directly enhances penile circulation. Increased blood flow supports firmer, more consistent erections and reduces the performance fluctuations that occur with hormone-related vascular decline. Many men report noticeable improvements in erection quality within weeks.
Enhance penile sensitivity
By rejuvenating nerve pathways and improving microcirculation, the P-Shot can significantly heighten sensation. This helps counteract the age-related loss of sensitivity often caused by hormonal shifts or reduced nerve function. Increased responsiveness can make intimacy feel more satisfying, natural, and enjoyable.
Support better orgasm quality
Sharper sensation, stronger erections, and improved blood flow often translate into more intense and fulfilling orgasms. Enhanced nerve signaling helps restore pleasurable feedback during sexual activity, especially for men who have noticed a decline in climax intensity.
May help with Peyronie’s disease
The growth factors in PRP have shown promise in softening scar tissue associated with Peyronie’s disease. By promoting tissue remodeling and reducing plaque density, the P-Shot may help improve curvature, reduce discomfort, and restore more natural function.

Potential improvement in size
Some men experience a modest increase in penile length or girth due to improved blood flow and regenerative changes in tissue. While results vary, the combination of healthier vascular structures and enhanced tissue response can create noticeable physical improvements.
Fast, non-surgical, and downtime-free
The P-Shot is performed in a simple in-office visit and requires no incisions, medications, or recovery time. You can return to your normal activities immediately after the treatment. Because the treatment uses your own blood, it is also highly safe and well-tolerated, making it an appealing option for men who prefer natural solutions.
Hormonal changes can deeply influence your sexual performance, sensitivity, and confidence, but they don’t have to define the quality of your intimate life. At Genesis Lifestyle Medicine, you have access to advanced hormone evaluation and regenerative treatments like the P-Shot that work with your body to restore strength, sensation, and long-lasting vitality. If you’re ready to feel more like yourself again, the path to better sexual health starts here.


