If you’ve been exploring options to improve your sexual health or restore stronger, more reliable erections, you’ve likely come across the P-Shot (Priapus Shot). This treatment uses your own platelet-rich plasma (PRP) to stimulate new tissue growth, increase blood flow, and enhance sensitivity. However, you may ask: How many times can you receive the P-Shot?
The short answer is: there’s no strict limit.
Many men repeat the treatment periodically to maintain their results. At Genesis Lifestyle Medicine, we specialize in customizing P-Shot protocols to your unique goals, physiology, and individual response. The frequency of treatments depends on how your body reacts, what you want to achieve, and how long you want the results to last.
Here’s a detailed look at what that means for you.
The optimal frequency of P-Shot sessions
When you first start P-Shot therapy, your body undergoes a natural process of regeneration. The growth factors in your PRP signal your body to repair blood vessels, nerves, and tissues in the penis. This takes time and consistency.
Most providers recommend an initial series of 1 to 3 P-Shot treatments, spaced 4 to 8 weeks apart. The idea is to build momentum in your cellular regeneration: the first injection jumpstarts the healing response, while subsequent ones strengthen and extend those effects. Many men start to notice improvements in erection firmness, sensitivity, and stamina after the first or second session, with results peaking several weeks later.
After completing this initial phase, your body will continue to produce new tissue and improve blood circulation over the following months. At this point, you can move into the maintenance phase to preserve and even enhance your progress.
The optimal maintenance schedule
P-Shot is not a one-and-done procedure. The results can last 6 to 18 months, depending on your overall health, hormone balance, and lifestyle habits. To maintain peak performance, most men schedule maintenance sessions every 6 to 12 months.
Some patients prefer to stay on a 6-month schedule to achieve optimal function. Others find that a yearly touch-up is enough to maintain results. Your doctor at Genesis Lifestyle Medicine will help you track your progress and determine when your next session should be.
You may also combine the P-Shot with other therapies like GAINSWave, testosterone optimization, or peptide therapy to extend your results further. These combination approaches can help sustain healthy blood flow, enhance libido, and improve recovery, allowing you to enjoy long-term performance without needing frequent injections.
Is there any limit to P-Shot treatments?
One of the biggest advantages of the P-Shot is that it uses your own platelet-rich plasma, making it incredibly safe. Because the treatment is entirely autologous (derived from your blood), there is no risk of rejection, allergy, or buildup of synthetic substances.
That means there’s no upper limit to how many times you can receive the P-Shot. Some men continue treatments for years as part of a proactive sexual wellness routine. The key factor is whether your body continues to respond well and whether your goals are being met.
Your Genesis Lifestyle Medicine provider will evaluate your progress after each round of treatment to ensure continued benefits. If your tissue response plateaus or if other underlying conditions (like hormone imbalance or cardiovascular issues) emerge, your provider might recommend complementary therapies or diagnostic testing to optimize your results.
Tips to maximize the P-Shot results
Maintain healthy testosterone levels
Optimal testosterone levels are crucial for libido, blood flow, and overall sexual function. Low testosterone can blunt the effects of regenerative therapies like the P-Shot. Your provider may suggest testosterone replacement therapy (TRT) or peptide support to help balance your hormones and enhance your body’s healing response.
Avoid smoking and excessive alcohol use
Nicotine constricts blood vessels and reduces oxygen flow to tissues, while alcohol can impair hormone production and overall blood circulation. Both habits interfere with the benefits of the P-Shot treatments. Reducing or quitting these substances can dramatically improve your long-term results and overall sexual health.
Stay consistent with exercise
Regular cardiovascular and resistance training promotes stronger blood flow and supports nitric oxide production, both of which are essential for erectile function. Aim for at least 150 minutes of moderate exercise per week. Activities like cycling, swimming, or weightlifting can help you maintain vascular health, ensuring optimal results from the P-Shot.
Follow a nutrient-rich diet
A balanced diet supports tissue repair and hormone balance. Include foods high in zinc, vitamin D, omega-3 fatty acids, and antioxidants, such as leafy greens, lean proteins, fish, berries, and nuts. These boost circulation and reduce oxidative stress over time.
Use the recommended post-treatment protocols
Your Genesis Lifestyle Medicine provider may recommend a penile pump or specific exercises to encourage blood flow and prevent tissue stiffness after treatment. These activities promote oxygenation and maximize PRP distribution in the treated area.
Manage stress and prioritize sleep
Chronic stress increases cortisol and lowers testosterone, both of which can interfere with healing. Prioritize 7 to 9 hours of quality sleep per night, and consider stress-reduction practices like meditation or breathing exercises to enhance hormonal and vascular balance.
You can safely receive the P-Shot multiple times, both as an initial series and for ongoing maintenance. Most men benefit from one to three initial sessions, followed by maintenance treatments every 6 to 12 months to sustain optimal results.
At Genesis Lifestyle Medicine, we believe in treating the whole person, not just the symptom. Our experts will design a customized P-Shot plan that supports your long-term vitality through comprehensive sexual wellness care. If you’re ready to maximize your performance, schedule your personalized consultation with Genesis Lifestyle Medicine today.
