If you’re an athlete or someone who trains hard, you know how it feels when your body just can’t keep up: the sluggish recovery days, the muscle soreness that lingers longer than it should, or that frustrating dip in stamina when you’re trying to perform at your best. Even with the perfect diet, training routine, and recovery strategy, your body may still struggle to produce enough cellular energy to meet your athletic demands.
NAD+ (nicotinamide adenine dinucleotide) is a vital molecule that plays a key role in energy production, muscle repair, and recovery: the very things your athletic performance depends on. At Genesis Lifestyle Medicine, we understand how crucial cellular health is for performance, which is why we offer science-backed NAD+ support to help you train harder, recover faster, and sustain your energy naturally.
Benefits of NAD+ for athletes
Enhances cellular energy production
Every movement, sprint, or lift your body performs depends on ATP, which is your body’s energy currency. NAD+ is essential for converting nutrients into ATP. When NAD+ levels are high, your cells generate energy efficiently, which sustains endurance and power output during workouts and competitions. Conversely, when NAD+ levels drop, energy production slows, causing you to become fatigued more quickly and limiting your performance potential. Supporting NAD+ can help ensure your body produces energy at its peak capacity, no matter how hard you train.

Speeds up muscle recovery and repair
After an intense training session, your muscles need to repair microscopic damage to grow stronger. NAD+ fuels this recovery process by activating key enzymes that support DNA repair and muscle tissue regeneration. It also helps clear out damaged cells and supports new, healthy cells. When your NAD+ levels are optimized with NAD+ therapy, your recovery time can shorten, soreness may decrease, and you’ll be ready to train again with less downtime: an essential advantage for athletes who push their limits daily.
Reduces inflammation and oxidative stress
Training at a high intensity produces oxidative stress: an excess of unstable molecules that can trigger inflammation and slow recovery. NAD+ helps regulate inflammation through its influence on sirtuins, a family of proteins that protect cells and reduce inflammatory responses. By supporting NAD+ levels, you help your body maintain a balanced inflammatory state, which can reduce fatigue, prevent overtraining, and protect long-term joint and muscle health.
Supports mental clarity and focus
Athletic performance isn’t just physical: it’s mental. Whether you’re on the field, in the gym, or on the track, focus and decision-making can make or break your performance. NAD+ supports mitochondrial health in brain cells, which improves concentration, mental endurance, and cognitive function. Maintaining optimal NAD+ levels can help you think faster, stay motivated, and maintain mental sharpness under pressure, all key factors in peak performance.
Promotes overall metabolic health
A strong metabolism is essential for building muscle, regulating weight, and maintaining consistent energy levels. NAD+ plays a crucial role in metabolism by influencing how your body converts nutrients into energy and utilizes fat and glucose efficiently. When NAD+ levels are supported, your body performs more effectively at both the cellular and metabolic levels, allowing for better energy balance, improved endurance, and lean muscle maintenance.

How to enhance NAD+ for improved endurance and recovery
Prioritize NAD+-rich nutrition
Certain foods naturally support your body’s ability to produce NAD+. These include those high in vitamin B3 (niacin), tryptophan, and nicotinamide riboside: nutrients found in foods such as salmon, mushrooms, chicken, dairy, and leafy greens. While diet alone may not completely restore depleted NAD+ levels, it provides a strong foundation to help your body sustain its natural NAD+ production. A well-rounded, nutrient-dense diet can also help stabilize energy levels and promote faster recovery.
Balance exercise and recovery
Training is necessary to improve performance, but overtraining can quickly deplete NAD+ stores. Consistent, moderate-intensity exercise has been shown to increase NAD+ levels over time, while inadequate rest does the opposite. The key is balance: alternating high-intensity days with recovery, prioritizing quality sleep, and incorporating mobility or stretching work. Allowing your body the chance to rebuild ensures your NAD+ stores stay steady and your performance continues to progress safely.
Manage stress and optimize sleep
Chronic stress and poor sleep are two of the fastest ways to drain your body’s NAD+ reserves. When you’re under constant stress, your body’s repair mechanisms work overtime, consuming NAD+ faster than it can be replenished. Quality sleep of around seven to nine hours per night gives your body the chance to rebuild and recycle NAD+. Incorporating relaxation techniques, such as deep breathing, meditation, or gentle stretching, before bed can go a long way in maintaining balanced energy levels.

Consider NAD+ therapy for targeted support
For athletes who need extra cellular support, Genesis Lifestyle Medicine offers NAD+ therapy through safe delivery options like patches, injections, and nasal sprays. These formulations can help replenish NAD+ more directly and efficiently than diet or supplements alone. By restoring your body’s NAD+ balance, these treatments may enhance recovery, improve metabolism, and support long-term performance goals. Every program is tailored to your unique training demands and recovery needs, ensuring that you get personalized results you can feel.
Whether you’re an endurance athlete, weightlifter, or weekend warrior, maintaining optimal NAD+ levels can have a profound impact on how you perform and recover. At Genesis Lifestyle Medicine, we believe true performance starts with cellular health. Our medical team specializes in helping athletes and active individuals harness the benefits of NAD+ through personalized therapies that boost endurance, recovery, and overall vitality. Contact us today to learn more about how NAD+ support can help you feel stronger, sharper, and more resilient.


