You may not think about your heart until something feels off: subtle fatigue, shortness of breath, or a sense that your stamina just isn’t what it used to be. Yet your heart is working for you every second of the day, delivering oxygen and nutrients to every cell in your body and keeping your entire system running smoothly. When your cardiovascular health begins to slip, the effects can ripple into your energy levels, mental clarity, and overall quality of life.
At Genesis Lifestyle Medicine, preventative, whole-body wellness is a core focus. That includes supporting your heart at the cellular level through advanced therapies like NAD+ alongside personalized lifestyle guidance. Understanding how NAD+ connects to heart health can help you take proactive steps toward a stronger, more resilient cardiovascular system.
What heart health really means
Heart health refers to the overall well-being of your cardiovascular system, including your heart, blood vessels, and circulation. A healthy heart pumps blood efficiently, thus allowing oxygen and nutrients to reach your organs and tissues while carrying away waste products.

When this system functions optimally, your body is better equipped to maintain stable energy, support brain function, and adapt to physical and emotional demands. Strong cardiovascular health plays a major role in reducing your risk of conditions like heart disease, hypertension, and stroke. It is not just about avoiding illness: it is about helping your body perform optimally.
Benefits of maintaining good cardiovascular health:
- Reduced risk of heart disease: A healthy cardiovascular system lowers your chances of developing coronary artery disease and other heart-related conditions that can compromise longevity and quality of life.
- Improved circulation: Efficient blood flow ensures that oxygen and nutrients are delivered where they are needed most, supporting muscle function, organ health, and overall vitality.
- Better blood pressure control: When your heart and blood vessels are functioning well, they are better able to regulate pressure, reducing strain on your arteries and lowering the risk of hypertension-related complications.
- Enhanced cognitive function: Your brain relies heavily on consistent blood flow. Good heart health is closely linked to better memory, focus, and mental performance.
- Improved mental well-being: Cardiovascular health and mental health are deeply connected. A healthy heart may help reduce stress, anxiety, and depressive symptoms, contributing to a more balanced sense of well-being.
The role of NAD+ in heart health
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in every cell of your body. It plays a central role in cellular energy production, repair processes, and metabolic function. Because your heart is one of the most energy-demanding organs, adequate NAD+ levels are essential for optimal cardiovascular performance.
Here’s how NAD+ supports heart health on a cellular level:
Supports cellular energy production
NAD+ plays a central role in converting the nutrients you consume into ATP, the primary energy source your cells use to function. Because your heart beats continuously, it has exceptionally high energy demands. Adequate NAD+ levels help ensure heart cells can consistently produce the energy they need to maintain strong, steady, and reliable contractions throughout the day.

Promotes mitochondrial function
Mitochondria are responsible for generating the majority of your cellular energy, and NAD+ is essential to keeping them working. When mitochondrial function is supported, heart muscle cells can produce energy more effectively, resist fatigue, and maintain optimal performance. Healthy mitochondria support stronger heart muscle contraction and better cardiovascular endurance.
Helps maintain blood vessel integrity
NAD+ supports the health of the cells lining your blood vessels, helping them remain flexible, resilient, and responsive. This contributes to smoother blood flow, better overall circulation, and improved delivery of oxygen and nutrients throughout your body. Well-functioning blood vessels place less strain on the heart and may reduce long-term cardiovascular risk.
Contributes to healthy aging
As you age, natural NAD+ levels gradually decline, which can impact energy production and cellular repair. Supporting NAD+ levels may help slow certain age-related changes within heart tissue, preserving cardiovascular efficiency. This cellular support can contribute to maintaining heart strength, endurance, and function as part of a proactive, healthy aging strategy.
Reduces oxidative stress and inflammation
NAD+ plays a role in cellular processes that help regulate oxidative stress and inflammatory responses. When these processes are better controlled, there is less damage to heart cells and blood vessels over time. This protective effect supports long-term cardiovascular health and may lower the risk of chronic conditions associated with inflammation.
How to increase NAD+ levels
Supporting your NAD+ levels does not require a single approach. A combination of lifestyle strategies and targeted therapies can help optimize your cellular health.

- Prioritize regular physical activity: Exercise naturally stimulates NAD+ production and supports mitochondrial function. Aim for a mix of cardiovascular exercise, strength training, and gentle movement throughout the week.
- Eat a nutrient-dense diet: Foods such as fish, poultry, whole grains, broccoli, cabbage, and leafy greens contain nutrients and precursors that support NAD+ production.
- Get consistent, quality sleep: Sleep is essential for cellular repair and metabolic balance. Poor sleep can disrupt NAD+ metabolism and compromise overall cardiovascular health.
- Manage daily stress: Chronic stress can increase inflammation and accelerate cellular aging. Practices like meditation or yoga may help protect both your heart and your NAD+ levels.
- Consider NAD+ therapy: At Genesis Lifestyle Medicine, NAD+ therapy is available through patches, injections, and nasal sprays. These delivery methods help support NAD+ levels. Your provider can determine the most appropriate option based on your health goals and needs.
Support your heart with Genesis Lifestyle Medicine
Your heart deserves proactive care. At Genesis Lifestyle Medicine, we take a comprehensive approach to cardiovascular and cellular wellness, combining advanced therapies like NAD+ with lifestyle guidance tailored to your unique needs. By supporting your heart from the inside out, you can move toward greater energy, resilience, and long-term vitality. Taking steps today to protect your heart can help you feel better now and for years to come. Contact us to schedule your consultation today.





