You’ve probably heard of Viagra: it’s one of the most common prescriptions for men dealing with erectile dysfunction (ED). Maybe it even worked for you at first. But over time, you’ve noticed that the results aren’t the same. You may still struggle to get or maintain an erection.

At Genesis Lifestyle Medicine, we specialize in science-driven solutions for ED that go beyond temporary fixes. In this article, you’ll learn why Viagra may stop working and the best alternative treatments available to help restore your sexual health and confidence.

Why Viagra may not work forever

Viagra (sildenafil) is a PDE5 inhibitor, a class of drugs that works by increasing blood flow to the penis. It blocks the enzyme that constricts blood vessels, making it easier for you to achieve and sustain an erection when sexually stimulated.

While effective for many men, Viagra doesn’t address the underlying causes of ED, such as low testosterone, nerve damage, poor circulation, or penile tissue changes. Over time, if those root issues worsen, the pill may lose its effectiveness. Additionally, your body can adapt to the medication, and the same dosage may no longer give you the results it once did.

Other common drawbacks with Viagra:

• Only works temporarily
• Requires planning before intimacy
• May cause headaches or flushing
• Can interact with heart medications
• Doesn’t improve penile tissue health
• May lose effectiveness with long-term use

The best ED treatments to try instead of Viagra

P-Shot (Priapus Shot)

The P-Shot is a breakthrough regenerative treatment that uses your own healing power to restore erectile function. It begins with drawing a small sample of your blood, which is processed to extract platelet-rich plasma (PRP). PRP is rich in natural growth factors that trigger tissue repair, stimulate blood vessel formation, and support nerve regeneration. When injected into specific areas of the penis, these growth factors activate cellular renewal and enhance circulation, helping to reverse the damage that contributes to erectile dysfunction.

Using PRP, the P-Shot works to rejuvenate your penis from the inside out. Unlike Viagra, which only increases blood flow temporarily, the P-Shot helps repair and strengthen the tissue itself. Many men experience firmer erections, heightened sensitivity, and in some cases, improvements in penile size and girth. It’s a safe procedure that promotes natural sexual function over time.

P-Long Protocol

The P-Long Protocol restores erectile strength and improves penile health and size over time. It combines multiple therapies: PRP to trigger regenerative repair, traction therapy to encourage natural tissue expansion, and medical-grade supplements to optimize vascular and hormonal support. This makes it one of the few ED solutions that address both performance and penile structure simultaneously.

The protocol stimulates stem cells, enhances collagen and elastin production, and promotes microcirculation. Over several months, these effects improve erection quality, stamina, and sensitivity. Unlike Viagra, which produces temporary results, P-Long builds a foundation for long-term improvements and can even contribute to increased penile length and girth.

GAINSWave shockwave therapy

GAINSWave uses low-intensity acoustic sound waves to restore penile blood flow and tissue health. These sound waves gently break up microplaque deposits in blood vessels, which can accumulate over time and limit circulation. As the plaque is cleared, the therapy also stimulates the body to grow new blood vessels, a process called neovascularization, which directly enhances erectile function.

This treatment is especially effective for men whose ED is caused by vascular issues like poor circulation or cardiovascular risk factors. Unlike pills, GAINSWave addresses the root cause by improving long-term penile blood flow. Over a series of treatments, many men notice stronger, more spontaneous erections, improved sensitivity, and restored sexual confidence.

TriMix injections

TriMix is an injectable therapy that provides rapid, reliable erections, even for men who don’t respond well to oral medications like Viagra. It contains a custom blend of three vasodilating medications (usually alprostadil, papaverine, and phentolamine), which are injected into the erectile tissue of the penis. These medications immediately relax smooth muscle and dilate blood vessels, causing an influx of blood that produces a firm erection within minutes.

TriMix is particularly useful for men seeking dependable results in situations where oral drugs fail or are contraindicated due to medical conditions. While it does not have the regenerative benefits of therapies like the P-Shot or GAINSWave, TriMix delivers predictable erections when needed. TriMix can produce on-demand results and offer greater control to men.

Find the right ED treatment for you

If Viagra has stopped working for you, it doesn’t mean your sex life is over. Pills provide only temporary relief and don’t address the root causes of ED.

At Genesis Lifestyle Medicine, we take a personalized, regenerative approach, whether through the P-Shot, P-Long Protocol, GAINSWave, or TriMix therapy. With today’s advanced treatments, you can reclaim control over your sexual health and experience results that are stronger, more natural, and longer lasting. Find a solution that truly works for you. Contact us to get started today.