You may have noticed a painful curve developing in your erection, or perhaps intercourse has become uncomfortable because of an unexpected bend or shortening of your penis. These changes can be worrying, leaving you not only with physical discomfort but also emotional distress that affects your confidence and intimate relationships.

This condition is known as Peyronie’s disease, and it affects thousands of men, particularly in midlife. The good news is that you don’t have to suffer in silence. At Genesis Lifestyle Medicine, we take a compassionate approach to helping men restore function. Understanding what causes Peyronie’s disease and how regenerative treatments like the P-Shot can help can empower you to take back control of your sexual health.

What is Peyronie’s disease?

Peyronie’s disease is a medical condition in which scar tissue, called plaque, forms inside the erectile tissue of the penis. This plaque is not cancerous, but it is fibrous and less elastic than normal tissue. As a result, when you get an erection, the hardened plaque prevents part of the penis from stretching normally, creating a curve or bend.

In some cases, this scar tissue may also cause pain, reduce penile flexibility, shorten the length of the penis, or make intercourse difficult. While mild cases can resolve on their own, more persistent cases can worsen and interfere significantly with your quality of life.

Common symptoms of Peyronie’s disease include:

• Noticeable curvature of the penis during erection
• Painful erections or discomfort during intimacy
• Shortening of the penis
• Loss of erectile rigidity in certain areas
• Difficulty with sexual intercourse
• Emotional distress and reduced confidence

What causes Peyronie’s disease?

The exact cause of Peyronie’s disease is not always clear, but most cases are linked to the abnormal healing of an injury to the penis. When the penis is bent or overstretched, small blood vessels and elastic fibers can rupture. Instead of healing normally, the injured area sometimes develops excessive scar tissue. This scar tissue hardens into a plaque, leading to curvature.

While trauma may trigger Peyronie’s disease, many men develop it slowly without recalling any specific injury. Factors such as reduced tissue elasticity with age, arterial disease, and certain medical conditions may increase susceptibility. Genetics also appears to play a role, as some men with Peyronie’s disease have family members with the same condition or related fibrotic disorders like Dupuytren’s contracture of the hand.

Risk factors for Peyronie’s disease include:

• Older age
• Family history of Peyronie’s disease
• Diabetes and metabolic conditions
• High blood pressure and cardiovascular disease
• High cholesterol and arteriosclerosis
• Smoking and excessive alcohol use
• Use of certain medications (e.g., beta blockers, antidepressants, antihistamines)

How can the P-Shot help?

The Priapus Shot, or P-Shot, is a non-surgical treatment that uses the body’s own natural healing abilities to restore penile health. The P-Shot is created from your own blood through a process that isolates platelet-rich plasma (PRP), a concentrated solution rich in growth factors and regenerative proteins. When injected into targeted areas of the penis, PRP stimulates repair, increases blood flow, and encourages the breakdown of scar tissue.

This makes the P-Shot an exciting option for men with Peyronie’s disease who are seeking a safe, regenerative treatment without the risks of invasive surgery. At Genesis Lifestyle Medicine, our providers specialize in administering the P-Shot with precision to maximize its benefits for both penile function and overall sexual wellness.

Here’s how the P-Shot can help with Peyronie’s disease:

• Stimulate natural tissue repair: The P-Shot’s growth factors promote cellular repair and regeneration. This process can soften and remodel the fibrous scar tissue responsible for Peyronie’s disease, gradually reducing curvature and improving flexibility.

• Improve blood flow and erectile function: Peyronie’s disease often comes with reduced erectile rigidity. By enhancing vascular growth and improving circulation, the P-Shot increases blood flow to the penis. This results in stronger, more sustainable erections.
• Reduce pain and discomfort: Scar tissue can create painful erections. The regenerative properties of the P-Shot help decrease inflammation and nerve sensitivity in the affected area, reducing pain during erections and sexual activity.
• Support penile length and girth preservation: Because Peyronie’s disease can shorten the penis over time, men often worry about lost size. The P-Shot’s ability to rejuvenate penile tissue and encourage elasticity helps in maintaining or even improving penile length.

Repair damaged tissue and restore function 

Living with Peyronie’s disease can feel discouraging, but it does not have to define your intimate life. With regenerative medicine, you have options beyond surgery. The P-Shot offers a natural way to repair damaged tissue and reduce the physical and emotional burdens of this condition.

At Genesis Lifestyle Medicine, we are committed to helping you reclaim your sexual health. If you’re experiencing symptoms of Peyronie’s disease, schedule a consultation and explore how the P-Shot can help you restore not only your erections but also your quality of life.