Zepbound®
Costa Mesa

Tailored to Your Needs

At Genesis Lifestyle Medicine, we offer Zepbound® in Costa Mesa as part of our personalized, physician-led weight loss plans. This innovative medication, also known as tirzepatide, may support long-term weight management by targeting multiple pathways involved in hunger and metabolism. Our Costa Mesa team works with you to develop a strategy tailored to your needs, empowering your journey toward better health.

May Help You Lose Up to 20% of Your Body Weight

Zepbound is a prescription-only treatment authorized by the FDA for adults classified as obese (BMI ≥30) or overweight (BMI ≥27) who also have at least one weight-related health condition. This medication is designed to simulate gut hormones that influence appetite and digestion, potentially helping reduce food intake and improve glycemic control. When used alongside a balanced diet and increased physical activity, patients may see weight loss approaching 20% of their starting body weight.*

At our Costa Mesa location, Zepbound is prescribed after a detailed in-person consultation to confirm its appropriateness for your individual profile. Our experienced team provides follow-up care to support your weight loss efforts every step of the way.

Why Choose Zepbound?

May help reduce appetite and cravings
Supports sustainable weight loss when paired with healthy lifestyle changes
Mimics gut hormones that play a role in metabolism
Promotes a longer-lasting sense of fullness after meals
Aids in managing blood sugar and insulin levels
May lower certain cardiovascular and metabolic risk factors
Approved by the FDA and evaluated in clinical studies
Prescribed in-person by licensed professionals
Delivered through a simple, once-weekly injection

healthy man jogging after Zepbound treatment in Costa Mesa

Understanding the Potential Side Effects

Possible side effects from Zepbound include nausea, vomiting, constipation, diarrhea, upset stomach, drowsiness, gas, injection site reactions, heartburn, hair thinning, and allergic responses. It should not be used by individuals with a personal or family history of medullary thyroid carcinoma (MTC) or those diagnosed with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). For detailed safety information, please refer to the official prescribing information at Lilly Zepbound.

How Zepbound Works

Zepbound acts on two specific hormone receptors—GLP-1 and GIP—that help regulate hunger and insulin response. These hormones are naturally released by the gut and communicate with the brain to signal satiety and delay gastric emptying. This dual action may help reduce food intake and improve post-meal satisfaction, making it easier to manage portions.

Additionally, Zepbound supports blood sugar stability and may enhance insulin sensitivity, making it a valuable tool for individuals with insulin resistance or those at risk for type 2 diabetes. By addressing multiple mechanisms of weight regulation, this treatment may contribute to gradual, consistent weight loss over time.

What to Expect with Zepbound in Costa Mesa

Your weight loss plan begins with a comprehensive health assessment at our Costa Mesa clinic, where we review your medical background, wellness goals, and relevant lab work. If Zepbound is a good fit, our team will guide you through its usage—from initial training to weekly injection routines.

You’ll administer Zepbound at home using a prefilled pen injector once a week. Dosing is personalized and typically begins at a low level, increasing gradually as your body adjusts. Throughout your treatment, we’ll monitor your progress and adjust the plan to help you stay on track.

Insurance and Coverage Details

Coverage for Zepbound varies by insurer and plan. Many private insurance providers may include it with prior authorization, and Medicare may cover it under specific circumstances. Our Costa Mesa office will assist you in exploring insurance benefits and determining your eligibility.

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You May Be a Good Candidate If You:

Have a BMI of 30 or higher
Have a BMI of 27 or higher and a related condition such as prediabetes or hypertension
Find it difficult to lose weight through diet and exercise alone
Prefer a non-surgical approach to weight management
Are dedicated to adopting long-term health habits
Do not have a history of MTC or MEN 2 syndrome

Clinical Outcomes of Zepbound Use

Research has shown that Zepbound, when used alongside a reduced-calorie diet and increased physical activity, can lead to meaningful weight loss outcomes.

In one clinical trial spanning 72 weeks, participants without diabetes lost an average of 15% (about 34 lbs) on a 5 mg dose, 19.5% (44 lbs) on a 10 mg dose, and 20.9% (48 lbs) on a 15 mg dose. Comparatively, the placebo group lost 3.1% (around 7 lbs). Individual results vary, and our Costa Mesa providers will work with you to set realistic expectations and monitor your response to treatment.*

man jogging after Zepbound treatment in Costa Mesa

Zepbound FAQs

How soon will I notice changes?

Some patients begin seeing changes within the first few weeks, especially when Zepbound is used with healthy eating and exercise. Most people observe more substantial progress between weeks 8 and 12.

Is this medication safe?

Zepbound has been evaluated in clinical trials and approved by the FDA. As with all prescription medications, it may cause side effects, which our Costa Mesa medical staff will monitor closely. You should always report any adverse effects that concern you.

How often do I need to take it?

Zepbound is administered once weekly using a prefilled injection pen. Injections are typically rotated between the abdomen, thigh, and upper arm.

What if I miss a dose?

If a dose is missed, take it within four days. If more than four days have passed, skip the missed dose and resume your regular schedule. Never take two doses within three days of each other.

*Individual results vary. In a 72-week Zepbound (tirzepatide) study of adults without diabetes, average weight loss was 15.0% (34 lbs.) for 5 mg, 19.5% (44 lbs) for 10 mg, 20.9% (48 lbs.) for 15 mg, and 3.1% (7 lbs.) for placebo. In a 72-week Zepbound (tirzepatide) study of adults with diabetes, average weight loss was 12.8% (28 lbs.) for 10 mg, 14.7% (33 lbs.) for 15 mg, and 3.2% (7 lbs.) for placebo.

Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, Kiyosue A, Zhang S, Liu B, Bunck MC, Stefanski A; SURMOUNT-1 Investigators. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med. 2022 Jul 21;387(3):205-216. doi: 10.1056/NEJMoa2206038. Epub 2022 Jun 4. https://pubmed.ncbi.nlm.nih.gov/35658024

The information provided on this website is not a substitute for professional medical advice. Always consult with a qualified healthcare provider for any questions about your health or treatment.

Zepbound® is a registered trademark of Eli Lilly and Company. This website is not affiliated with, endorsed by, or sponsored by Eli Lilly and Company. All trademarks and brand names are property of their respective owners. Use of these names, logos, and brands does not imply endorsement Genesis Lifestyle Medicine. Information about Zepbound is sourced from publicly available materials and is intended for educational and informational purposes only. All rights to such content belong to the respective company.

Zepbound®
Costa Mesa

Tailored to Your Needs

May Help You Lose Up to 20% of Your Body Weight

Why Choose Zepbound?

Understanding the Potential Side Effects

How Zepbound Works

What to Expect with Zepbound in Costa Mesa