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May Help Patients Lose Up to 20% of Body Weight*

Zepbound is an FDA-approved treatment indicated for weight loss in adults living with obesity, or those who are overweight with at least one weight-related health condition. It acts by mimicking natural gut hormones that influence hunger, satiety, and blood sugar regulation. When paired with nutritional guidance and increased physical activity, some individuals may experience weight reductions of up to 20% of their starting weight.*

At our Greenwood clinic, your journey begins with a thorough consultation to determine whether Zepbound is a suitable part of your treatment strategy. Our in-person care ensures you're supported every step of the way.

Potential Benefits of Zepbound

Zepbound may offer a number of supportive effects that contribute to weight loss and metabolic health:

  • May help reduce appetite and manage food cravings
  • Can support meaningful and gradual weight loss over time
  • Mimics gut hormones to assist with metabolic function
  • Increases satiety to promote smaller portion sizes
  • Helps regulate blood sugar and insulin response
  • May aid in reducing cardiometabolic risk factors
  • FDA approved and validated through clinical trials
  • Prescribed in-person by trained medical professionals
  • Delivered via a convenient once-weekly self-injection
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What Side Effects Might Occur?

As with many prescription medications, Zepbound may cause side effects. These can include nausea, constipation, diarrhea, vomiting, abdominal discomfort, indigestion, gas, hair thinning, fatigue, redness at the injection site, allergic reactions, and heartburn.

Zepbound should not be used by individuals (or their family members) with a history of medullary thyroid carcinoma (MTC) or those with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). For full safety details, refer to the official prescribing information: Zepbound Full Prescribing Info.

How Zepbound Works to Support Weight Loss

Zepbound activates two hormone receptors: GLP-1 and GIP. These receptors are involved in the body’s natural regulation of hunger, digestion, and blood sugar. By enhancing signals that tell the brain you are full, and slowing gastric emptying, Zepbound may reduce the desire to overeat. This dual-action approach contributes to lower calorie intake and weight reduction over time.

Additionally, it may improve insulin sensitivity and help manage blood glucose levels—particularly beneficial for individuals with insulin resistance or prediabetes. By influencing multiple mechanisms related to metabolism, Zepbound creates a comprehensive response that may support long-term weight loss efforts.

What to Expect from Your Greenwood Zepbound Program

Your experience begins with a personalized consultation at Genesis Lifestyle Medicine in Greenwood. During this visit, we evaluate your health history, weight loss goals, and relevant labs to determine if Zepbound is appropriate for your situation.

If prescribed, you’ll receive hands-on guidance on using a prefilled pen for weekly injections, typically administered in the abdomen or thigh. The dosage begins at a lower level and gradually increases, allowing your body to adjust while minimizing side effects. Our providers are available throughout your treatment for ongoing support and monitoring.

Insurance Coverage for Zepbound

Coverage varies depending on your insurance provider. Some commercial health plans may include Zepbound with prior authorization, and Medicare may offer coverage for qualifying conditions. Our staff can help clarify your plan’s options and guide you through any required steps.

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Who Might Qualify for Zepbound in Greenwood?

You may be eligible to use Zepbound if you meet the following criteria:

  • BMI of 30 or higher (obesity)
  • BMI of 27 or higher with related conditions such as type 2 diabetes or hypertension
  • Difficulty losing weight through diet and exercise alone
  • Seeking a non-surgical medical weight loss solution
  • Ready to adopt long-term lifestyle changes
  • No personal or family history of MTC or MEN 2

How Much Weight Do Patients Typically Lose?

Clinical trials suggest that Zepbound, when used alongside a lower-calorie diet and regular exercise, can lead to substantial weight reduction.*

Participants in a 72-week study without diabetes lost an average of:

  • 15.0% (34 lbs) on a 5 mg dose
  • 19.5% (44 lbs) on a 10 mg dose
  • 20.9% (48 lbs) on a 15 mg dose

Those on a placebo lost an average of 3.1% (7 lbs). However, results vary, and your provider will help determine realistic expectations based on your medical profile.

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Zepbound FAQs

When will I start to see results?

Some patients begin noticing changes in appetite or weight within the first few weeks. More significant progress is often seen between 8 to 12 weeks with consistent use and adherence to lifestyle changes.

Is Zepbound considered safe?

Zepbound has undergone extensive clinical testing and is FDA-approved. While it’s generally well-tolerated, some individuals may experience side effects. Serious risks include the potential for thyroid tumors. Our Greenwood providers will discuss all safety considerations during your evaluation and provide continued support during your treatment.

How do I take it?

Zepbound is injected once a week using a simple, prefilled pen. Injection sites rotate between the abdomen, thigh, and upper arm.

What if I miss a dose?

If a dose is missed, take it within 4 days. If more than 96 hours have passed, skip the missed dose and resume your regular schedule. Do not double up doses within 3 days of one another.

Begin Your Greenwood Weight Loss Journey Today

Genesis Lifestyle Medicine is proud to offer in-person prescriptions for Zepbound in Greenwood as part of our individualized weight loss programs. From your first consultation to your ongoing progress, we’re here to support your health goals with compassion and expertise. Schedule your visit today to explore whether Zepbound might be a valuable part of your weight loss strategy.

*Individual results vary. In a 72-week Zepbound (tirzepatide) study of adults without diabetes, average weight loss was 15.0% (34 lbs.) for 5 mg, 19.5% (44 lbs) for 10 mg, 20.9% (48 lbs.) for 15 mg, and 3.1% (7 lbs.) for placebo. In a 72-week Zepbound (tirzepatide) study of adults with diabetes, average weight loss was 12.8% (28 lbs.) for 10 mg, 14.7% (33 lbs.) for 15 mg, and 3.2% (7 lbs.) for placebo.

Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, Kiyosue A, Zhang S, Liu B, Bunck MC, Stefanski A; SURMOUNT-1 Investigators. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med. 2022 Jul 21;387(3):205-216. doi: 10.1056/NEJMoa2206038. Epub 2022 Jun 4. https://pubmed.ncbi.nlm.nih.gov/35658024

The information provided on this website is not a substitute for professional medical advice. Always consult with a qualified healthcare provider for any questions about your health or treatment.

Zepbound® is a registered trademark of Eli Lilly and Company. This website is not affiliated with, endorsed by, or sponsored by Eli Lilly and Company. All trademarks and brand names are property of their respective owners. Use of these names, logos, and brands does not imply endorsement Genesis Lifestyle Medicine. Information about Zepbound is sourced from publicly available materials and is intended for educational and informational purposes only. All rights to such content belong to the respective company.

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