How GLP-1–Based Therapies Function
GLP-1–based medications, including tirzepatide, act on hormonal pathways that help regulate appetite and glucose metabolism. Tirzepatide engages both GLP-1 and GIP receptors, two incretin hormones involved in how the body processes food intake.
These pathways contribute to signaling fullness, influencing insulin and glucagon activity, and supporting post-meal blood sugar regulation. By acting on these receptors, GLP-1–based therapies may influence appetite-related signaling and digestive processes in some individuals. The nature and extent of these effects vary widely and represent just one element of a broader, medically supervised wellness plan that may also include nutritional guidance, physical activity recommendations, and behavioral support.
Individual responses differ, and no specific changes in appetite, weight, or metabolic measures can be promised.
