If you’re considering the P-Shot (Priapus Shot), it’s completely natural to wonder, “Does it hurt?” After all, it involves an injection in a sensitive area. However, most men who undergo the P-Shot report only minimal discomfort. Thanks to the use of numbing agents and the expertise of trained medical professionals, the experience is typically far less painful than expected.

At Genesis Lifestyle Medicine, we take a patient-first approach to all sexual wellness treatments, ensuring you know exactly what to expect before, during, and after your P-Shot appointment. Below, we’ll break down whether the P-Shot hurts, what happens during the treatment, and what the recovery process looks like.

Does the P-Shot hurt?

The short answer is: not really. Most men are surprised by how comfortable the procedure actually is. The P-Shot is administered using a very fine needle, and before the injection even begins, a powerful numbing cream is applied to the penis to reduce sensitivity. In some cases, a local anesthetic may also be used for added comfort. By the time the injection is administered, the area is usually sufficiently numb that you feel little more than mild pressure or a slight pinch.

Some men describe the sensation as a quick sting or momentary discomfort, but it typically lasts only a few seconds. At Genesis Lifestyle Medicine, we take every precaution to ensure you’re relaxed throughout the process. If you're particularly sensitive or anxious, we offer additional options to help manage discomfort and make the experience as smooth as possible.

What to expect during the P-Shot?

The P-Shot procedure is quick, minimally invasive, and typically takes less than 30 minutes from start to finish. Here’s a step-by-step breakdown of what you can expect:

1. Consultation: Your provider will begin with a brief consultation to review your goals, medical history, and any concerns you may have. This is your opportunity to ask any questions.
2. Numbing: A topical numbing cream is applied to the penis and allowed to sit for 15-20 minutes. In some cases, a local anesthetic may be used for additional pain control.
3. Blood draw: A small amount of your own blood is drawn, similar to what you’d experience during a standard blood test.
4. PRP preparation: The blood is then placed in a centrifuge, which separates the PRP from the rest of the blood. PRP is rich in growth factors that help stimulate tissue regeneration.
5. Injection: The PRP is carefully injected into targeted areas of the penis. Because of the numbing agents used beforehand, most men report little to no pain during this step.
6. Post-treatment guidance: After the injection, your provider may guide you through a short protocol using a penis pump to help maximize results and support blood flow.

What to expect after the P-Shot?

Although the P-Shot is minimally invasive, it’s still a medical procedure. It’s important to know what you might experience in the hours and days following treatment so you can care for yourself properly and optimize your results:

• Mild soreness or swelling: It’s common to experience some mild soreness, swelling, or tenderness at the injection sites. This typically resolves within one to two days. Over-the-counter pain relievers like acetaminophen can help manage any discomfort, but you should avoid medications like ibuprofen or aspirin, which can interfere with platelet activity.
• Minimal downtime: There’s little to no downtime required. You can return to work or your regular routine the same day, although it’s advisable to avoid strenuous exercise or sexual activity for the first 24 to 48 hours. Your provider at Genesis Lifestyle Medicine will provide you with clear post-treatment instructions tailored to your specific needs.
• Gradual improvement in function: The results from the P-Shot aren’t immediate. You may start noticing improvements in sensitivity, firmness, or erectile function within a few days to a few weeks. Most men experience optimal results about 3 to 6 weeks post-treatment, as the body fully responds to the regenerative effects of the PRP.

• Possible bruising: Some men experience minor bruising in the treated area. This is a temporary side effect and not a cause for concern. The bruising usually fades within a few days and does not interfere with the effectiveness of the treatment.
• Recommended use of a penis pump: To enhance the effects of the P-Shot, your provider may recommend using a penis pump for a few minutes each day over the next few weeks. This helps encourage better circulation and maximizes the benefits of the PRP.

While the idea of getting an injection in such a sensitive area might sound intimidating, the P-Shot is surprisingly comfortable for most men. At Genesis Lifestyle Medicine, we’re committed to helping you reclaim confidence and intimacy through evidence-based treatments like the P-Shot. If you're curious about whether this regenerative solution is right for you, schedule a consultation with our team today.