Semaglutide, the active ingredient in Wegovy, is a medication originally developed to treat type 2 diabetes. However, during clinical trials, researchers observed a notable side effect: significant weight loss. This led to further studies, and in June 2021, the FDA approved Semaglutide for weight management under the brand name Wegovy. Semaglutide works by mimicking the hormone GLP-1, which regulates appetite and food intake, helping individuals feel full longer and reducing overall calorie consumption.
When taken as prescribed, Semaglutide is administered as a weekly injection, making it convenient for those seeking a long-term solution for weight loss. By slowing down the digestive process and suppressing appetite, Semaglutide aids in creating a calorie deficit, a crucial component for weight loss. Combined with lifestyle changes such as diet and exercise, this medication can be a powerful tool in the fight against obesity.
How many pounds a week can you lose on Semaglutide?
The amount of weight you can lose with Semaglutide depends on several factors, including your starting weight, adherence to lifestyle changes, and how your body responds to the medication.
The STEP trials (Semaglutide Treatment Effect in People with Obesity) have shown promising results. In STEP 3, participants who received 2.4 mg of Semaglutide weekly lost an average of 16% of their starting body weight over 68 weeks. This translates to approximately 1-2 pounds per week, depending on individual starting weights and compliance with the treatment regimen. In comparison, the placebo group only lost about 5.7% of their body weight.
In STEP 4, participants continued with Semaglutide for an additional 48 weeks. Those who stayed on the medication maintained their weight loss, averaging a total reduction of 17.4% of their initial body weight. These studies highlight that consistent use of Semaglutide can lead to sustainable weight loss, with weekly averages varying based on individual circumstances.
Tips to boost weight loss results with Semaglutide
While Semaglutide can aid in weight loss, optimizing its effectiveness involves incorporating various lifestyle changes and strategies. Here are some tips to help you maximize your results:
- Follow a balanced, low-calorie diet: Maintaining a balanced, low-calorie diet is crucial to enhancing the weight loss effects of Semaglutide. Aim to consume between 1200 and 1500 calories daily, focusing on nutrient-dense foods. Incorporate plenty of low-GI carbohydrates like whole grains and lean