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Reduce Weight Effectively

At Genesis Lifestyle Medicine in Frisco, we offer Zepbound® (tirzepatide) as part of our in-person medical weight loss solutions. This innovative treatment may help patients reduce weight more effectively by addressing multiple metabolic processes. Each program is individually designed by our healthcare professionals to support your long-term health and weight management goals.

Potential Weight Reduction with Zepbound

Zepbound is a prescription-only medication approved by the FDA for weight loss in adults who have obesity or who are overweight and also have at least one health condition related to weight. It works by mimicking hormones found naturally in the digestive tract to curb appetite, enhance satiety, and support glucose control. When used alongside proper nutrition and consistent physical activity, Zepbound has been shown to promote weight loss of up to 20% in some patients.*

At our Frisco clinic, we provide comprehensive assessments to determine if Zepbound is right for you and monitor your progress closely for safe, sustainable results.

Genesis Lifestyle Medicine

Why Frisco Patients Choose Zepbound

  • May reduce hunger and manage food cravings
  • Supports meaningful, ongoing weight reduction
  • Emulates gut hormones to encourage better metabolism
  • Enhances feelings of fullness after eating
  • Helps regulate blood sugar and insulin activity
  • May help lower risks associated with conditions like heart disease and type 2 diabetes
  • Approved by the FDA and supported by research studies
  • Only prescribed after an in-person consultation
  • Given once weekly via injection

Possible Side Effects of Zepbound

Some individuals may experience side effects such as nausea, vomiting, diarrhea, constipation, indigestion, tiredness, injection site reactions, allergic responses, bloating, hair thinning, and acid reflux. 

Zepbound is not recommended for individuals who have or have had a type of thyroid cancer known as medullary thyroid carcinoma (MTC) or who have a rare endocrine condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Visit Zepbound’s official safety page for more complete information.

How Zepbound May Contribute to Weight Loss

Zepbound works by activating GLP-1 and GIP hormone receptors in the body. These receptors are involved in regulating appetite and blood sugar. When triggered, they send signals to the brain that can reduce feelings of hunger, slow digestion, and increase the sensation of fullness—allowing individuals to eat less and feel more satisfied. This process may support weight loss when used in conjunction with lifestyle changes.

The medication also helps stabilize blood sugar levels and improve how the body uses insulin, which can be especially useful for people with insulin resistance or at risk for type 2 diabetes. By working through more than one metabolic pathway, Zepbound offers a multifaceted approach to weight management.

What to Expect with Zepbound in Frisco

During your visit to our Frisco location, we’ll review your medical history, perform a physical evaluation, and order any necessary lab tests to see if Zepbound fits your health profile.

If you’re a good candidate, we’ll provide training on how to administer the weekly injection using an easy-to-handle, prefilled pen. The dose is gradually increased under provider supervision to help minimize side effects while improving effectiveness. Most injections are done in the thigh or abdomen.

Does Insurance Cover Zepbound?

Coverage for Zepbound varies depending on your health insurance plan. Some commercial plans may include it with prior authorization. In certain cases, Medicare may also provide coverage for qualifying individuals. Our team in Frisco can assist you in checking your insurance benefits and understanding your options.

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Who Might Qualify for Zepbound?

You may be a candidate if you meet any of the following:

  • BMI of 30 or above (classified as obesity)
  • BMI of 27 or above with a related health issue like type 2 diabetes
  • Ongoing struggles with weight loss despite efforts
  • Interested in a non-surgical medical weight loss treatment
  • Ready to commit to meaningful changes in lifestyle habits
  • No personal or family history of medullary thyroid cancer

How Much Weight Could You Potentially Lose?

Clinical studies have shown that individuals who used Zepbound in combination with lifestyle modifications lost significantly more weight than those using a placebo.

  • 5 mg dose: ~15% average body weight loss (approx. 34 lbs)
  • 10 mg dose: ~19.5% average loss (approx. 44 lbs)
  • 15 mg dose: ~20.9% average loss (approx. 48 lbs)
  • Placebo group: ~3.1% average loss (approx. 7 lbs)

These outcomes are based on a 72-week clinical trial. Individual results will vary, and the best way to assess if Zepbound could work for you is to consult with one of our Frisco providers.

Genesis Lifestyle Medicine

Zepbound FAQs

How soon could I see results?

Many patients notice early changes in weight within a few weeks, especially with consistent use alongside healthy eating and exercise. More noticeable progress usually appears between 8–12 weeks.

Is Zepbound safe?

Zepbound is FDA-approved and was evaluated in large-scale clinical trials. Like all medications, it may cause side effects and isn’t appropriate for everyone. Your Genesis provider will work closely with you to monitor your health and help manage any issues.

How often is Zepbound taken?

Zepbound is injected once per week using a prefilled pen. You should rotate between injection sites like the upper arm, abdomen, or thigh.

What if I forget a dose?

Take the missed dose as soon as possible within 96 hours (4 days). If more than 96 hours have passed, skip that dose and resume your regular schedule. Never double up or inject two doses within three days of each other.

Schedule Your Frisco Zepbound Consultation

Genesis Lifestyle Medicine in Frisco offers Zepbound injections as part of our physician-guided medical weight loss programs. From your first consultation to your weekly injections, our team will be with you every step of the way—providing individualized support to help you move forward on your health journey. Contact us today to learn whether Zepbound may be a suitable option for you.

*Individual results vary. In a 72-week Zepbound (tirzepatide) study of adults without diabetes, average weight loss was 15.0% (34 lbs.) for 5 mg, 19.5% (44 lbs) for 10 mg, 20.9% (48 lbs.) for 15 mg, and 3.1% (7 lbs.) for placebo. In a 72-week Zepbound (tirzepatide) study of adults with diabetes, average weight loss was 12.8% (28 lbs.) for 10 mg, 14.7% (33 lbs.) for 15 mg, and 3.2% (7 lbs.) for placebo.

Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, Kiyosue A, Zhang S, Liu B, Bunck MC, Stefanski A; SURMOUNT-1 Investigators. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med. 2022 Jul 21;387(3):205-216. doi: 10.1056/NEJMoa2206038. Epub 2022 Jun 4. https://pubmed.ncbi.nlm.nih.gov/35658024

The information provided on this website is not a substitute for professional medical advice. Always consult with a qualified healthcare provider for any questions about your health or treatment.

Zepbound® is a registered trademark of Eli Lilly and Company. This website is not affiliated with, endorsed by, or sponsored by Eli Lilly and Company. All trademarks and brand names are property of their respective owners. Use of these names, logos, and brands does not imply endorsement Genesis Lifestyle Medicine. Information about Zepbound is sourced from publicly available materials and is intended for educational and informational purposes only. All rights to such content belong to the respective company.

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